Differences in Gene Conversion Rates among Exons Between HLA-A and HLA-B Loci.
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چکیده
منابع مشابه
Epistasis among HLA-DRB1, HLA-DQA1, and HLA-DQB1 loci determines multiple sclerosis susceptibility.
Multiple sclerosis (MS), a common central nervous system inflammatory disease, has a major heritable component. Susceptibility is associated with the MHC class II region, especially HLA-DRB5*0101-HLA-DRB1*1501-HLA-DQA1*0102-HLA-DQB1*0602 haplotypes(hereafter DR2), which dominate genetic contribution to MS risk. Marked linkage disequilibrium (LD) among these loci makes identification of a specif...
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ژورنال
عنوان ژورنال: The Kurume Medical Journal
سال: 1999
ISSN: 0023-5679,1881-2090
DOI: 10.2739/kurumemedj.46.79